Small Molecule Inhibitors of Bromodomain-Acetyl-Lysine Interactions

Small Molecule Inhibitors of Bromodomain-Acetyl-Lysine Interactions.

Brand, M.; Measures, A.; Wilson, B.; Cortopassi, W. A.; Alexander, R.; Hoss, M.; Hewings, D. S.; Paton, R. S.; Conway, S. J. ACS Chem. Bio. 2015, 10, 22–39

You might also like
Investigations on Recyclization and Hydrolysis in Avibactam Mediated Serine B-Lactamase Inhibition
Dioxygen Binding in the Active Site of Histone Demethylase JMJD2A and the Role of Protein Environment
Cation–Pi Interactions in CREBBP Bromodomain Inhibition: An Electrostatic Model for Small-Molecule Binding Affinity and Selectivity
Natural Product Biosynthesis: It’s All Downhill from Here
A New Mechanism for Beta-Lactamases: Class D Enzymes Degrade 1-Beta-Methyl Carbapenems via Lactone Formation
Quantum Mechanical Calculations Suggest That Lytic Polysaccharide Monooxygenases Employ a Copper-Oxyl, Oxygen-Rebound Mechanism
Modeling catalysis in allosteric enzymes: Capturing conformational consequences
Enzymatic Catalysis of Anti-Baldwin Ring-Closure in Polyether Biosynthesis